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Chlamydia trachomatis infection in genitourinary tract has been increased recently and regarded as one of the most important sexually transmitted disease. A clinical study was presented of 458 patients who visited the OPD of the Department of Obstetrics and Gynecology, Ewha Womans University Hospital from April, 1989 to March, 1990 and an analysis was made by enzyme immunoassay (Chlamydiazyme test, Abatt Laboratories) in endocervix. We compared the 40 cases of C. trachomatis positive group with those of same number of negative group selected by random sampling among 418 negative cases which were participated in this study. The results were as follows; 1. The positive rate of C. trachomatis was 8.7%(64 of 458 cases). 2. Age distribution of C. trachomatis positive group was highest in the 20∼29 years range (45%). There was a significant difference in mean age between C. trachomatis positive group and negative group (30.3 years vs. 36.2 years, p<0.01). 3. Parity distribution of C. trachomatis positive group was highest in the nulliparous woman, but those was no significant differences in parity and abortion between C. trachomatis positive and negative group. 4. In gram staining of vaginal discharge, gram positive cocci was found to be highly significant in the C. trachomatis negative group compared with that of positive group. 5. The most common clinical symptoms in the C. trachomatis positive group was vaginal discharge, and others were lower abdominal pain of lumbago, vulva it ching sensation, urinary symptoms and infertility in the order of named. Clinical findings of C. trachomatis positive group were purulent vaginal discharge, cervical erosion, fundal tenderness, adnexal tenderness but were not significantly different from those of C. trachomatis negative group. 6. C.trachomatis positive group was more likely to be using contraceptive methods such as intrauterine device, oral pill condom compared with C. trachomatis negative group, but significance was not found between these two groups.
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